Neurônios de mosquitos recém-descobertos podem ser únicos para humanos

10/09/2018 12:25:00​​​​​​​
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Neurônios de mosquitos recém-descobertos podem ser únicos para humanos. Usando ferramentas transcriptômicas, morfofisiológicas e de bioinformática, uma equipe internacional... ​​​​​​​

As bactérias no nosso intestino produzem eletricidade

20/09/2018 21:00:00​​​​​​​
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Alguns tipos de bactérias comumente consumidas ou já encontradas em nosso intestino podem gerar eletricidade, segundo um novo estudo publicado na edição de 12 de setembro do Journal Nature.

Credit: Amy Cao graphic. Copyright UC Berkeley.​​​​​​​

Nutraceuticals targeting lipolysis could confer additional cardiovascular benefits, genetic analysis finds

28/09/2018 21:00:00​​​​​​​
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Alleles in the lipoprotein lipase pathway that lower triglyceride levels work independently of genetic mechanisms that lower low-density lipoprotein cholesterol levels, according to a new study.

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Genetic study identifies five forms of type 2 diabetes

30/09/2018 12:25:00​​​​​​​
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Patients with type 2 diabetes, based on their genetic variants, can be grouped into five clusters that reflect different disease mechanisms and could help personalize treatments in the future, according to a new study.

Novel system uses AI to detect abnormalities in fetal hearts

02/10/2018 12:30:00​​​​​​​
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A research group led by scientists from the RIKEN Center for Advanced Intelligence Project (AIP) has developed a novel system that can automatically detect abnormalities in fetal hearts in real­ time using artificial intelligence (AI).

Credit: www.uhdoctor.org/news/ohio-s-first-fetal-heart-procedure-performed-at-uh-rainbow-babies-and-children-s-hospital

Researchers use ZFNs to edit mutation in mitochondrial DNA in vivo

01/10/2018 17:00:00​​​​​​​
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Mutations in mitochondrial DNA (mtDNA) can cause a significant number of diseases, but these disorders are currently difficult to treat. However, using a recently developed mouse model that recapitulates common molecular features of heteroplasmic mtDNA disease in cardiac tissue

KAIST researchers develop heart ­targeting drug delivery technology using tannic acid

04/10/2018 15:00:00​​​​​​​
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Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones. To efficiently treat cardiovascular and related vascular diseases without surgery, a KAIST research team developed a heart ­targeting drug delivery technology using tannin acid via intravenous systemic injection.

Credit: https://kazzit.com/wine

USC research uncovers previously unknown genetic risk factor for dementia

03/10/2018 14:25:00​​​​​​​
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New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. The study provides insights on how these conditions, and other diseases of aging, might one day be treated and prevented.

Credit: www.frontiersin.org/articles/10.3389/fendo.2014.00210/full

Study sheds light on how brain protein may be involved neurodevelopmental disorders

05/10/2018 20:30:00​​​​​​​
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In the brain, nerve cells maintain interaction with other neurons through the expression of certain proteins on their membranes. However, surface proteins that stay on the membrane for too long can disrupt the connections between synapses.

Aging may have originated at the very beginning of life, says study

29/10/2018 09:30:00​​​​​​​
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A new USC Dornsife study indicates that aging may have originated at the very beginning of the evolution of life, at the same time as the evolution of the first genes. "This could be a game changer for research on longevity and aging.

Researchers have confirmed research on how to slow aging even late in life

06/10/2018 11:25:00​​​​​​​
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Previous research published earlier in 2018 in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was...

Credit: bit24/Fotolia

How 'bad' bacteria gain an upper hand in the human gut

28/10/2018 13:30:00​​​​​​​
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The bacteria produces a compound called para­cresol that promotes its survival by disrupting the growth of other intestinal microorganisms. The authors hope this unique compound could provide a target for the development of drugs to treat C. difficile.

Body organs undergo structural changes in response to diet

30/10/2018 11:45:00​​​​​​​
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Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie's Rebecca Obniski, Matthew Sieber, and Allan Spradling.

Study highlights opposite effects of gene following different types of environmental events

30/10/2018 21:30:00​​​​​​​
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Researchers have discovered that the same gene which increases your risk of depression following financial stress as you grow older also reduces your chance of depression associated with friendship and relationships stresses when young­ your social network.

Credit: https://www.thebestbrainpossible.com

Researchers show possibility to restore insulin cell function in type 2 diabetes

01/11/2018 10:30:00​​​​​​​
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By blocking a protein, VDAC1, in the insulin­ producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease.

Credit: drugtargetreview.com

Researchers identify neurons essential for normal sleep

01/10/2018 12:45:00​​​​​​​
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Two decades ago, Clifford B. Saper, MD/PhD, Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center (BIDMC), and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep.

Credit:  Science Source/Getty Images

Scientists discover new molecular pathway that controls colorectal cancer development

02/10/2018 08:30:00​​​​​​​
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Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have discovered a new molecular pathway that controls colorectal cancer development, and their exciting findings open new therapeutic opportunities.

New blood test may detect early­ stage lung cancer when surgical intervention is not possible

02/11/2018 10:30:00​​​​​​​
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Non ­small­ cell lung carcinoma (NSCLC) is often fatal because most cases are not diagnosed until they are so advanced that surgical intervention is no longer possible. To improve outcomes researchers are developing a blood test to detect lung cancer earlier in the disease.

Credit: Vasudha Murlidhar, Nagrath Lab, University of Michigan

New method for studying the cell nucleus could improve disease detection

03/10/2018 12:45:00​​​​​​​
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The method, which was described in the journal Physical Review Letters, could offer a new way of understanding the physical properties of diseased cells such as those seen in Parkinson’s or Alzheimer’s disease.

Credit: Christina Caragine and Alexandra Zidovska, Department of Physics, New York University